Cellular Energy and Its Link to Common Health Conditions

02:08-08:39What is Cellular Energy and why is it so important? 
09:14- 12:57Hormonal dysfunction, fatigue and cellular energy
13:00-17:00Cellular energy and the importance of healthy muscle mass
17:23 –22:40What can be done to Improve cellular energy and mitochondrial function? 
25:14-30:35How do you measure mitochondrial function?
30:38 – 34:33Injection therapies for mitochondrial dysfunction 
34:34 – 41:41Healthy and want to stay that way? Seek the help of a naturopath!
41:49- 44:12Viruses, infections and Cellular Energy 
50:19 – 54:27The top tips to boost immune function with Naturopath Dr. Bryan Rade! 

Dr. Clayton Roach: [00:00:06] All right, well, let’s get going again. Welcome to Hump Day Conversation Number 46 with Dr. Bryan Rade and Dr. Boudreau and me, Dr. Roach, and we have the honour and privilege of having Dr. Rade again, who has been more than willing to dedicate and donate his time. I should say for three conversations, this is his third one, so I’m sure we saved the best for last. No pressure. People have been raving about the last two. As Ben said, you can find those on YouTube, on our channel. It’s easier to browse those than to look through the Facebook post.

Obviously, because we got tons of content on there. And you can also check out Dr. Bryan Rade Facebook page, which you could also find them over there. So first of all, for those of you who do not know who Dr. Bryan Rade is, let’s just start with a quick introduction. Who’s Dr. Bryan Rade? What gets him excited? Go ahead.

Dr. Bryan Rade: [00:01:10] Ok, so I’m a doctor, I’ve been practicing for 12 years. Well, first in Lower Sackville, in Bedford for the past six years now or so. And yeah, what gets me excited is working with patients with complex chronic illnesses. Patients with neurological disorders, chronic infections. Lyme disease and related infections like mould illness, children on the autism spectrum. Also, children deal with a neuropsychiatric condition called pandas or pans. I work with a lot of patients with cancer diagnoses. I treat a lot of patients with pain like sports injuries. Arthritis and things like that with different injection therapies. Those are the things that get me excited. So just helping really tough cases to get better.

What is Cellular Energy and why is it so important? 

Dr. Clayton Roach: [00:01:57] Awesome. And for tonight, we chose a topic that I’m not too familiar with. I understand the concept around it. We’re going to do a little bit of a deep dove into cellular energy. Maybe we can start off kind of bringing everybody up to speed as to why this topic is so important. Then we’ll dive into some of the parallels in terms of the diseases. and stuff that might have that as a precursor in terms of a cause is that the cell doesn’t have the energy it needs in order to provide the environment for us to be happy. So let’s maybe just kind of everybody bring everybody up to snuff in terms of why is this topic important? The topic of cellular energy?

Dr. Bryan Rade: [00:02:46] Sure. Our chat this evening is quite timely. In two days I am presenting at our annual Nova Scotia naturopathic conference. I’m going to be speaking about mitochondrial dysfunction or in our cellular energy production capacity is compromised. For the title of my presentation, I came up with the title and tried to remember the exact title. But it’s something to the effect of mitochondrial dysfunction, a unifying feature of all disease question marks. And I feel like it’s not a question mark. I think it is a unifying feature of all diseases. How important is the ability to make cellular energy? It’s incredibly important. You really can’t name a condition or a disease that isn’t characterized by impaired cellular energy dysfunction.

Outside of a traumatic injury, virtually any illness or disease state you can name likely has mitochondrial dysfunction. It is a key component of cellular energy production to function as a key component of that condition. Or it’s at least in an indirect way, contributing to that pathophysiology. It’s crucially important when I realize that flippantly in my practice. I really only came to that realization a few years ago. It really turned my practice around and it really helped me to bring better care to my patients. I was already doing well, but it just really took my practice to the next level.

Dr. Clayton Roach: [00:04:37] Yeah, so for those of you who don’t know, but you know, obviously the energy that we have in the form of correct me, if I’m wrong in the form of ETP, everything comes from the cell. The cell is unable to produce it. Obviously, the deficiency is going to show up in other deficiencies because so many other factors depend on it. So how is that applicable, like in terms of like hands-on approach?

Dr. Bryan Rade: [00:05:19] Yeah, it’s a great question, so it really kind of depends on what the condition is, so one of the easiest to discuss conditions as it relates to mitochondrial dysfunction is fatigue. So, so many folks, of course, out there has fatigue. When you look at the list of all the various symptoms that are associated with almost any syndrome or disease or disorder you can name, fatigue is a feature of almost any one of them. And so it’s a really common affliction. Even for folks who don’t have a specific disease or pathology. If they’re not eating optimally or exercising properly, they might feel more tired than they’d like to. It’s hard to find someone who says, I’ve got exactly how much energy I’d like to have.

And that energy is, as you touched on, it’s all about what your cells are producing. Our cells have these little structures in them called mitochondria. Depending on the cell type, a cell could have hundreds or thousands or millions of mitochondria per cell. The way to kind of think about it is if your cell is a big watermelon. It thousands of little black seeds in it. Those little black seeds would all be the mitochondria.

Dr. Bryan Rade: [00:06:32] And so the mitochondria make that ATP. That’s, as you said, cellular energy. Ultimately, if the cells are not making enough of that ATP you’re going to feel tired. When a person says I feel tired, they mean their mitochondria aren’t making as much ATP as the cells need. Therefore, I’m experiencing this energy depletion. So to answer your question, how does that actually look tangibly with a patient like in a patient encounter? It’s really asking the questions. I’m asking the questions on my mind.

Do this patient’s mitochondria have all the resources it needs to make energy? Can talk about what some of those resources might be in terms of various vitamins and minerals, amino acids, antioxidants? But then also, is there anything standing in the way of these mitochondria working properly? Because we all know that heavy metals like lead and mercury are bad for us. We all know that pesticides and herbicides and different, you know, synthetic chemicals are bad for us. We know that say mould toxins are bad for us.

Dr. Bryan Rade: [00:07:35] We know that chronic viral infections are bad for us. What’s fascinating to me is that I see all these things in my patients. They are all mitochondrial poisons. When people are inundated with too many chemicals and heavy metals, they have chronic viral infections. They have mould exposure and persistent Lyme disease or chronic Lyme disease. They feel tired and go figure because these things are poisonous to the mitochondria. The question is this person tired because they’re missing some of the nutrients needed to run the mitochondria?

Are they feeling tired because their mitochondria are being poisoned and therefore can’t work properly? The third and final possibility is the managers of the mitochondria. Does it centre on certain hormones in our bodies? Are they not working properly? Those are really the three reasons why a person could have mitochondrial dysfunction and subsequent fatigue. And I’ll leave it there because I could just go on and on and on.

Dr. Clayton Roach: [00:08:40] Oh boy, I tell you, I think we need a little thumbs up on that one. That was, that’s great. I never heard it explained that way. Bryan, that’s a really good way of explaining that. And like the watermelon analogy and all that.

Dr. Bryan Rade: [00:08:56] Go ahead, Ben. Thank you. I was just doing it.

Dr. Ben Boudreau: [00:09:01] I was just going and blown away, especially by, you know, all the different parameters that that sort of play into it. I want to touch on the hormonal aspect, right? Because we talked about how there are three main causes. I’d like to talk a little bit about the hormonal aspect. Which conditions might come out of that type of dysfunction, or maybe the other way around?

Hormonal dysfunction, fatigue and cellular energy

Dr. Bryan Rade: [00:09:25] Sure. The main hormones that are going to impact mitochondrial function are cortisol from your adrenal glands. Thyroid hormone from your thyroid. And then all of your sex hormones, your estrogen, progesterone, testosterone and DHEA. And so those and a vitamin D is also really important for mitochondrial function. It’s technically a hormone. We’ll just kind of pretend that it’s no separate category. Also, melatonin, which is technically a hormone neurotransmitter. It’s also really important for mitochondrial function as well, but just kind of keeping it simple and talking about cortisol.

Thyroid hormone and then your sex hormones. Essentially, they tell the mitochondria what to do and when to do it. So if a person has something that’s negatively impacting their thyroid gland-like, say, they have an iodine deficiency or, interestingly enough, iodine excess can cause certain thyroid pathologies more like autoimmune pathologies, for example, or if a person has an issue with their adrenal glands because they’re just too stressed, they’re burning the candle at both ends. Or they’ve been through a lot of traumatic experiences, or they’re just chronically sleep deprived because they’re they’ve been in naturopathy practice for 12 years and have three boys at home and take on too many side projects.

I don’t know anybody like that, but that that might do a number on somebody’s adrenal glands, that those are situations where like, oh, the mitochondria might start becoming dysfunctional because the adrenal is just have been essentially overtaxed and they’re not kind of controlling things optimally or maybe a person who’s going through menopause, there’s maybe some hormone shifting or pre-existing hormone imbalances. And so menopause kind of like comes in like a lion instead of a lamb, so to speak. And so that could cause a lot of issues with energy or sleep disruption or various things like that. So. So that’s kind of some examples of how hormonal dysfunctions could ultimately or certain circumstances could lead to the dysfunction or issues with the glands or the organs that are making those hormones and then ultimately impacting mitochondrial function.

Dr. Clayton Roach: [00:11:31] So Dr. Rade in that case, like when you’re taking a look at the symptoms from the hormonal dysregulation, so to speak, and some of the symptoms that come from that is the symptom from lack of production of ATP, from the mitochondria. So let’s say, you know, the upper managers are not allowing the mitochondria to produce. ATP is the number one symptom of that process, always fatigue along with the other symptoms from the hormonal problem.

Dr. Bryan Rade: [00:12:03] Not necessarily, I mean, yeah, like if you had say, like insufficient levels of estrogen-like that might lead to hot flashes or that might lead to saying like vaginal dryness, or it might lead to predispose to osteoporosis or something like that. So those are all symptoms that are, of course, not fatigue. I mean, those are all symptoms that I’m sure if somebody studied it, they’d probably find that it has a mitochondrial underpinning in terms of, say, like osteoporosis, for example. And that’s actually really interesting if you start looking into osteoporosis and seeing that there is a mitochondrial dysfunction underlying component of that.

But the long and short of it is that sometimes you will see symptoms that don’t fatigue for sure when there are those lower levels of those hormones. But I think there’s probably a mitochondrial dysfunction underpinning with some of those other non-fatigue symptoms that might pop up.

Dr. Clayton Roach: [00:12:58] Well, it’s really interesting.

Cellular energy and the importance of healthy muscle mass

Dr. Ben Boudreau: [00:13:00] Now Dr. Rade is the greatest source of ATP in the in like the cells that are in the muscles because they normally say, you know, like people that are really, you know, like really big and, you know, strong, these are the people with the most amount of mitochondria, so they’re bound to have the most amount of energy. Are we seeing these cellular issues in these types of people?

Dr. Bryan Rade: [00:13:27] So I mean, you could like I mean, you can certainly have like people with a lot of muscle mass certainly could be fatigue or have symptoms of mitochondrial dysfunction, but they’d be less prone to those issues. I think a more muscle mass is generally associated with better health outcomes and overall health. It’s really interesting, in my opinion when you look at the breakdown of which tissues have the highest energy consumption at which it turns out are your skeletal muscle. So just for folks listening, so like three types of muscle, there’s your skeletal muscle, which moves your bones around.

There’s your smooth muscle, which lines your digestive tract and your urinary tract, and kind of these involuntary like subconsciously controlled muscles. And then as your cardiac muscle in your heart and so skeletal muscle that moves are body parts around that has about that’s responsible for about 20 percent of all of our energy expenditure when we’re at rest. Our brain uses about 20 percent as well in our liver uses about 20 percent. So those are the three biggest energy consumers.

But what’s interesting is that when you look at the density of which tissues have the highest amount of mitochondria in them, or rather like when you look at the volume of rather when you look at a certain cell type and see what percentage of that cell volume is consumed or filled up with, it’s the heart is the top one. That’s forty-three percent of the heart is those heart cells that are filled with mitochondria. It’s the densest source of mitochondria in the body. And yet the heart doesn’t make the top three list in terms of energy consumption.

Dr. Bryan Rade: [00:15:10] So it’s one could look at that and say, Well, is that because if your heart gives out, then you’re going to give out. And so therefore you want to have a lot of redundancy and have lots of mitochondria just in case some of them give out like i.e., if you have a clot in it, it’s blocking your blood flow to your heart and you want to make sure that heart’s going to survive as much as possible. But or, you know, you look at the mitochondrial density in brain cells and it makes up something like five percent of the cell volume. Like, it’s relatively small, even though the brain is using up about 20 some odd percent of the energy throughout the day.

There’s sort of sometimes a disparity between the density of the mitochondria in the cell versus how much energy is being consumed. But the long and short of it is that if you have more muscle mass, you will have a better metabolism to ultimately be making more energy. You’re just going to have essentially a better metabolism there for better cell turnover. One of the things that are really important in the body, as best we can tell from the research that’s been done is a person who has more what’s called autophagy or mitophagy happening. Autophagy means like a breakdown of old cells, which makes room for new cells, essentially or mitophagy, in which we break down old mitochondria to make room for new mitochondria that seems to be associated with better health outcomes, and you’d likely see that in someone with more lean muscle mass.

Dr. Ben Boudreau: [00:16:31] Yeah, and I was about to ask if we would have to be more lean muscle versus someone who is bulk and bulk season, which a lot of people are entering the bulk season at this point. And so just making, you know, again, just throwing another point towards the towards, you know, the importance of strength and resistance training, as well as just good aerobic exercise to keep the muscles again creating new tissue instead of just replacing it with fat tissue.

Dr. Clayton Roach: [00:17:01] Yeah, for those of you just joining in, we are live with Dr. Bryan Rade with Sunday conversation number forty-six, we’re talking mitochondria and cellular energy. If you like this episode so far and you just join in, please give us a little bit of a sign of thumbs up or heart. I know a lot of you are patients of ours, and I hope you’re liking this. Dr. Reed, can you talk about the other two scenarios we talked about the upper management and what could affect how the mitochondria can work and the other two scenarios that you presented?

What can be done to Improve cellular energy and mitochondrial function? 

Dr. Bryan Rade: [00:17:32] Yeah, so one of those other scenarios is, do the mitochondria have all of the nutrients that it needs in order to make energy? For those of us on the call who had to suffer through not only high school biology but undergraduate biology, then first-year medical school? Whether it’s chiropractic, naturopathic, all of us have to go through even more biology, and we have to oftentimes memorize all the steps involved going through what’s called the glycolysis pathway, then the Krebs cycle then the electron transport chain and memorizing all the enzymes as I’ll never need to know that again.

In all fairness, in clinical practice, you don’t really need to know all that stuff, but it’s probably good to have memorized it at least a few times. It’s stuck in that brain somewhere. But basically, all of those many steps, all of those chemical reactions, many of them require certain nutritional factors in order to work properly. It is kind of like little helper nutrients to allow them to work as efficiently as possible. Then there are also certain things referred to as substrates that are required. Like raw material or infrastructure materials that are required for all those reactions to happen as well. What I did not know until my first year of natural Catholic school, and either I was just snoozing in a classroom, I just didn’t think to mention it in my undergrad and I did an undergrad in biology.

Dr. Bryan Rade: [00:18:52] It was a little odd that I didn’t pick this up until naturopathic school. But the reason that we need certain B vitamins that people talk about, they’re not going to take a B complex. I have more energy. It’s like, Well, how do B how to B vitamins have anything to do with energy production? Well, to make energy in your mitochondria, you need b 1 b to b 3 b 5 b 6. I mean, you ultimately do need b 12 and folate as well, folate being sometimes referred to as B nine. But the long and short of it is all the B vitamins are ultimately some of them. Crucially, well, they’re all crucial, but some of them are very directly needed for energy production in the mitochondria, some of the more peripherally needed for energy production in the mitochondria.

We need all of our B vitamins. There are certain minerals that we need. We need magnesium, we need zinc. We need manganese. In order for our copper, we need iron. We need sulphur for our mitochondria to function properly. Acids that we require for our mitochondria to work properly. One called taurine, one called carnitine, one called proline. And then we also need antioxidants for our mitochondria to work properly. Vitamin C, vitamin E coenzyme Q10 melatonin is crucially important for our mitochondrial function, something called glutathione. So there’s this myriad list of nutrients that are required in order for the mitochondria to work properly.

Dr. Bryan Rade: [00:20:14] And if a person is low in one or more of those then their mitochondria are not going to work properly. The analogy I use with my patients all the time is that it’s like making a recipe like so baking a cake that has 15 different ingredients in it. And if you’re missing even one ingredient, I mean, it depends on the ingredient flour, then oh man, that’s not going to turn into a cake. If it’s salt, it’s like, OK, it’ll still turn into a cake. It just might taste a little bit off. But if you’re missing certain ingredients, especially core ingredients, you’re going to have a really hard time making energy very efficiently.

It’s one of the approaches that I use in my practice and something that was kind of part of that game-changing paradigm shift for me a few years ago was the difference between you. Plus mitochondrial support versus comprehensive mitochondrial support. So once upon a time, I would say it’s like, Oh, a person has low energy, I want to spread their mitochondria. Let’s work with the B complex. Maybe let’s get a multi-mineral in there and maybe just leave it there. And sometimes that works great. Sometimes it didn’t work that great. In hindsight, a lot of those patients actually required other nutrients as well, and not to spoil the punch line, but there’s not really fantastic testing to determine what the levels of all those nutrients are like in the patient’s body.

Dr. Bryan Rade: [00:21:30] And so rather than being able to say, Oh, let’s just run this great lab test and see exactly what we need to supplement you with, it’s actually quite a bit more cost-effective and efficient to just supplement with all of the things that mitochondria need. We figured out a very concise, cost-effective way of doing that that doesn’t require taking like twenty-five different supplements, which is always nice. And then just seeing it basically marinating the patient’s mitochondria in all of those nutrients that they might need if that helps their mitochondria to feel better. And hormonal managers are working well as long as there are not too many toxins or poisons that are afoot. Poisoning the mitochondria then might get comprehensive.

Mitochondrial support can work incredibly well for people, and a lot of folks, myself included, who are already feeling good, oftentimes comprehensive mitochondrial support, they’ll find that they feel even better. So like before I started taking it, I was, you know, felt like I was about. I was very happy with how I felt like, you know, nine, 10 out of 10 energy brains working well, all that good stuff. I went on mitochondria support, and I would say I felt probably like a 10 or 15 percent boost in how I felt overall taking it personally. So I take it every morning before I go to work just for good measure.

Dr. Clayton Roach: [00:22:42] Cool. So that is something that anybody can take, Bryan Dr. Bryan Rade, Dr. Rade. They don’t have to be worried about any contraindications or anything like if they just prophylactically, they just want to feel better. That’s a concoction that they would be able to take.

Dr. Bryan Rade: [00:22:58] Yeah, there could be contraindications. I mean, the way that we operate at my clinic is like we sell supplements and things like that. But we don’t have like any kind of like a storefront kind of operation like my staff. They know only to sell supplements to existing patients and whatnot. So I certainly don’t recommend comprehensive mitochondria support just as like a blank like, oh yeah, like just like everybody, pretty much everybody could like take, you know, vitamin D, for example, it’s like they’re generally speaking there. They’re very safe nutrients and that they’re vitamins, minerals, amino acids, antioxidants. So for the most part, if you don’t need them, then your body is just going to excrete whatever you don’t need.

But there are some patients where we certainly do need to be really cautious with it because one of the many reasons I love the comprehensive mitochondrial support is that it’s it also covers all of the bases for patients. Phase one and phase two liver detoxification pathways support as well. So if a patient came to me and said, I want to go on super-comprehensive liver detox support and say, Hey, you know, we can use the mitochondrial support formula, it’s kind of like a two for one, again, remembering that about 20 percent of our resting energy expenditures through the liver.

Dr. Bryan Rade: [00:24:15] Well, guess what that means. It means the liver needs to be making a lot of ATP in order to function properly. The subtext to that is if a patient has detoxification issues or they have a lot of stored toxins, sometimes if they start on too much mitochondria sport too quickly, they’ll actually start feeling crummy. Like, Oh my gosh, like I’ve got diarrhea or my breath is really bad or my skin is breaking out, or I’m feeling more tired or headache or brain fog because they’re actually detoxifying excessively.

It’s generally speaking, it’s a very safe, supplemental approach to work with. There really aren’t significant contraindications to taking any of the ingredients there, but we do have to be careful with how we ramp up the dosing and what the patient’s history is like and all that before embarking on a comprehensive mitochondria support protocol.

Dr. Clayton Roach: [00:25:06] Cool. Yeah. And you did mention it’s hard to there’s not like one comprehensive test that you can do to try to figure out how the mitochondria are working. No. That’s tough. That’s where you get the expertise.

How do you measure mitochondrial function?

Dr. Bryan Rade: [00:25:22] Uh, yeah, well, that does help. The expertise was and nice, and for sure there are some tests for mitochondrial function. What I said earlier was that there’s no, in my opinion, no definitive test for measuring your levels of all of those nutrients that I mentioned. Granted, there’s half-decent testing for B12, half-decent testing for folate. There’s good testing for vitamin D and iron. Testing for anything else isn’t great, in my opinion. Some tests that you can run like you can drop hundreds of dollars on nutrient profiles and panels. And I, as I say, oftentimes to my patients or to my colleagues, like I want those tests to be super accurate because how amazing would it be for everybody if it was like, Wow, those tests are really accurate and it just tells us exactly what you’re low in.

But whenever we ask those companies and say, Hey, like, can you just send us your reproducibility trials meaning like you ran the test on one hundred people and then a week later, or even a day later, you ran the exact same tests on them again with no intervention in between and show me the data showing me that the results are basically like 90 percent the same, meaning that you’d prescribe the same things to each person today and then a week later, i.e. a reproducibility trial. And they don’t have that data because they’ve never done it before. It’s like, Well, that’s interesting.

Dr. Bryan Rade: [00:26:46] How is that test useful in any way, shape or form? Like I’ve got to test, it’s a lot cheaper. It’s called flipping a coin. They might as well just see like, are you high or low in vitamin A by doing that? And so again, I want the testing to work, and I and I know some of my colleagues use that testing, and I’m not saying that it’s not clinically useful. I just don’t run the test because I’m not confident that the test is actually reproducible and they’re just so darn expensive.

And then at the end of the day, when I look at, quite frankly, the cost of using comprehensive mitochondrial sport, like using it all on one formula, it’s so much cheaper than buying every individual ingredient that even if I saw the 15 ingredients in this mitochondrial support, you only need five of them when you price it out. Oftentimes, it’s more expensive to buy the five individuals.

So just putting on my thinking cap as I try to bring that to work with me every day, I think, you know what? Let’s save money on the testing. Let’s maybe wait till they finally run some reproducibility trials, and let’s just do comprehensive support instead. There is some testing that is available to assess mitochondrial function. I’m happy to talk about that if you’d like to hear about it or we can. Yeah, sure. So there are a few tests that have been developed to assess mitochondrial function.

Dr. Bryan Rade: [00:27:59] There’s no one test that can assess every facet of mitochondrial function mentioned. There are so many steps involved and actually making the energy in the cell, in the mitochondria. But one of the tests that have the most clinical utility and I’ve used it with a number of patients over time is something called an organic acid test. Organic acids are basically these metabolites that are produced in the body, and they get excreted in the urine and they’re in the blood as well. And basically, measuring those metabolites gives us insight into different physiological processes in the body. But one of those physiological processes is how the mitochondria organic acids are actually intermediates in what’s called the Krebs cycle.

So kind of one of those steps in the ATP production and the mitochondria. And so we can measure those levels. And with organic acid testing, it hasn’t been rigorously studied to the extent that I’d like it to be studied. But there’s just so much clinical use with it that I found it to be a useful test in my patient. So if we want to run an objective test to get a sense of how a person’s mitochondria are doing, then that’s one of the better tests to run, in my opinion, and in my experience. But there is a test that I think is even more useful and accurate than the organic acid test. And that’s what I like to call the.

Dr. Bryan Rade: [00:29:24] Are you feeling tired test? And if a patient says yes, I’m feeling tired, then that means that their mitochondria are not functioning optimally because all the energy in the body comes from the mitochondria. And so if a person says my energy is not exactly where I want it to be, it means like, Oh, you’ve got mitochondrial dysfunction. We maybe need to figure out why. But that’s a really nice test because it costs zero dollars and you can run it as many times as you want. You could check it every week, you could check it every day. It’s just asking the person, Are you feeling tired? And so as they’re feeling better, then it’s like great. The therapy is working. So again, I do like I love lab testing. I’m a big lab geek.

I worked in a cell biology lab for a couple of years back in my undergrad. It’s great. It’s not nearly as much fun as practicing with patients, but like, you know, practicing naturopathic medicine with patients. But it’s great. But I mean, an organic acid test with the U.S. exchange rate because there are no Canadian labs that do it. You’re looking at a good like. Three hundred and fifty bucks give or take. It’s pretty expensive, so I talked to my patients about the options. If they want to do the testing, that’s great. We’ll do it. Otherwise, we can just use the retired test and that works really well, too.

Injection therapies for mitochondrial dysfunction

Dr. Clayton Roach: [00:30:36] Awesome. So Dr. Rade, when you test for mitochondria and it comes back and you know there is a problem is the solution give or take that mitochondrial complex that you give them? Or are there injection therapies that you can do for that as well?

Dr. Bryan Rade: [00:30:54] So yes, there are IV therapies that could be used as an adjunct. One of the there is two therapies that are the most directly useful for supporting the mitochondria. One is doing what we call a high-dose nutrient infusion, and that’s basically where we’re using high dosages of all the B vitamins, minerals, amino acids, and then we actually add in intravenous ATP. So it’s really cool is we can actually give cellular energy intravenously, which is, I think, kind of fascinating. I learned about that from another naturopathic colleague. I was shadowing probably about seven or eight years ago, it is C and I’d never heard of it before.

And lo and behold, there’s, you know, information about it in the scientific literature, and it can be really helpful. It can really make like make the difference between the IV nutrients having a modest major. So the high-dose nutrients are a way of helping to jack up the levels of all those mitochondria sports nutrients faster. And I always view IV therapy as being kind of like an accelerator pedal and that it will get you to. Oftentimes it will get patients to the finish line faster. But it’s relatively rare that IV therapy is quote-unquote mandatory. Like that, it’s absolutely necessary to get a person to achieve their health goals, but it can be really helpful to get them there faster. So it’s one of the reasons that we use IV therapy.

Dr. Bryan Rade: [00:32:18] The other IV that can be really useful is, um, intravenous ozone therapy, which we talked about, I think, a couple of months ago. And so for folks who weren’t on that call, the ozone therapy basically helps to bring more oxygen into the body’s tissues, and it does many other things as well. Anti-inflammatory immunomodulating, tissue healing. It’s amazing stuff. But when it comes to all the nutrients that are required for the mitochondria to function, there’s only one that we can’t put in a supplement bottle, and that’s oxygen. Now, thankfully, we’re breathing in oxygen every minute of every day, but to supersaturate the cells with oxygen, you can’t do that orally.

At least I’m not aware of being able to do that. I mean, there are like, Oh, here’s like oxygen drops and this and that, and I’ve not been privy to any information to suggest that actually works in any meaningful way. But I’ve ozone therapy definitely boosts up cellular oxygen levels. And then the other therapy that can do that is hyperbaric oxygen therapy. But in my clinical experience, the ozone works quite a lot better for achieving that, for boosting up mitochondrial function. So IV nutrients and intravenous ozone, which is kind of like intravenous oxygen, are typically the most useful therapies to bolster mitochondrial function.

Dr. Clayton Roach: [00:33:39] Nice. Can you give us an idea, Dr. Rade, in terms of pricing where that would come from?

Dr. Bryan Rade: [00:33:45] Yeah. With high dose nutrients, the total cost which includes the cost of my colleagues, the time who runs the IVs for me and the cost of the nutrients themselves, it’s about one hundred and fifty dollars per treatment. There’s no tax on that. And then for ozone therapy, it’s about one hundred and twenty-five dollars for the cost of the materials for that. No tax on that as well for some patients will do both together. And so if we’re doing the nutrients and the ozone at the same time, then it’s one hundred and ninety dollars per treatment in total. So you kind of if you’re if basically if you’re already sitting in the IV chair, then it’s really just kind of ala carte for the cost of materials over and above for four additional IVs that we’re running, so to speak.

Healthy and want to stay that way? Seek the help of a naturopath!

Dr. Ben Boudreau: [00:34:34] What are the indications to see a naturopath if the patient doesn’t present with any symptoms, they’re happy with their visits to their internal doctor? What would be the other indications, maybe, that someone would want to seek the help of an octopath? Such as yourself.

Dr. Bryan Rade: [00:34:51] That’s great that’s a really great question. One of my favourite types of patients to work with just because I need a little break from the difficulty sometimes is like, Hey, I’m feeling really good and I just want to stay that way. It’s wonderful when that happens. One of the reasons to consider seeing a naturopathic doctor when you’re already feeling good is just to try to stay feeling good. What I would do within that type of situation is I would talk to the patient about running some labs to see what’s going on kind of under the hood, so to speak, because, in my opinion, there’s really two really important pieces of information to know if somebody is healthy.

One is asking them, like, How are you feeling? And if somebody feels really good, then that’s, I would say, the most important bit of information. But the other information would be, well, how do you look inside? And of course, somebody like that probably has totally normal-looking standard lab tests from there, say, their family doctor or whoever they were working with. They’re not anemic. Their livers aren’t inflamed, their kidneys aren’t malfunctioning. They’re not falling apart at the seams. As I’m fond of saying, standard blood work really helps to rule out serious pathology. So it’s super, super important. But you can be feeling pretty crummy and have totally normal-looking blood work, and you’ll have 75 percent of my patients that I see will say I’ve had every test under the Sun.

Dr. Bryan Rade: [00:36:13] I’m so healthy on paper, but I feel like garbage today. And so it’s, you know, it’s standard. Blood work is fantastic, but it’s good at what it does, but it’s not going to cover all the bases that a patient might need. So there are some really useful functional lab tests. So one of my favourite tests to run is something called a cardiometabolic panel. It measures inflammation levels in the body. It tells us things about antioxidant levels in the body, tells us about blood sugar regulation with a lot of detail, tells us. Vascular health with a lot of detail tells us about the patient’s homocysteine level, which is an important marker that tells us about this really important biochemical set of reactions that happen to the body called the methylation cycle.

So we get a ton of useful data about a number of different systems in a person’s body when they run a cardio metabolomic profile like that. Another test that I like to run on patients who are healthy and want to stay that way is doing a genomic profile where we basically do a genetic test and see do they have any mutations at certain key locations of certain genes that code for the enzymes that run everything in the body? So that can tell us about their ability to make certain antioxidants, so tells us about their ability to make certain antioxidants like glutathione and catalase and superoxide dismutase.

Dr. Bryan Rade: [00:37:31] And then also for anyone who’s listening that really likes to geek out on antioxidants. That’s something called Nerf two and keep one which are kind of these master control Occident expression. The genomic testing tells us about different cardiovascular risk factors, gives us more insight into the function of the patient’s methylation cycle. Tells us about their ability to activate certain vitamins, like their ability to turn inactive B12 into the active form or inactive folate into the active form, or inactive or precursor molecule to vitamin A into the active form of their histamine metabolism. Just the list goes on and on, so we can get a lot of really useful information with that genomic testing.

I also in patients who are healthy and want to stay that way, will oftentimes recommend at some point along the way that they do some heavy metal testing just to see if they have elevated heavy metals in their body or not. So that’s another common test that will run because sometimes folks who have led a very like non you’d think a very non-heavy metal exposure existence, meaning they are, you know, they have an office job, they live in a, you know, they don’t, I don’t know, they’re not coal miners like they’re not soldering lead pipes as.

They’re not shooting bullets at the shooting range all the time, getting exposed to lead that way. Some folks with histories like that, like just typical like, you know, just lived in a suburb and an office job and you know, it just, I don’t know, I play tennis and like, that’s it.

Dr. Bryan Rade: [00:38:58] They sometimes have sky-high levels of heavy metals. And so it’s really, I think, good to look into whether there’s something like that going on. And sometimes we run the tests on patients and we see, Oh, you’re not sky high, but you’re higher than you should be. So why don’t we start lowering the levels of those? Because elevated heavy metals like a lot of chronic illnesses. So I think that’s an important test to run as well. So those are, I would say, those are probably my top three tests that I would talk about. But there are other things too, like making sure that that patient has. They’re eating a healthy diet.

There may be thinking about things that can help to kind of biovar their way into a better state of health. They may be doing some cold exposure therapy, or they may be looking at different breathing techniques like Utako breathing or Wim Hof breathing. Are they possibly trying different diet changes, like maybe doing some periodic intermittent fasting, maybe doing a crazy carnivore diet here or there, and checking different things like that to make sure they’re getting good sleep? Because some people say, I feel really good, but like, yeah, I’m only getting six hours of sleep because I spend an hour and a half on my phone, on social media before I go to bed. Because lots of people do that.

Dr. Bryan Rade: [00:40:06] It’s like there could be little things like that that I might be screening for just to help to try to encourage their overall better health and longevity. And one of the things that I think is exciting about mitochondrial dysfunction, and I’m actually speaking about this at another conference in about a month, is looking at the link between mitochondrial dysfunction and ageing. And there have been a number of theories of why we age. Why is it that we look and feel different at 20 versus at 80? To my understanding, the prevailing theory, like the one theory that has not been shot full of holes over time, is the mitochondrial theory of ageing.

Essentially, there’s a very strong case that’s been made to say that when you have mitochondrial dysfunction that perpetuates the ageing process. And so by keeping our mitochondria nice and happy and healthy, it should help us to have not only, I think, very likely a better life, like a longer lifespan, but a better healthspan, which if you ask somebody like, do you want to live to 90 and feel just wretched for the last 30 years of your life? Or do you want to live to eighty-five and feel amazing until your last day? It’s like, I think most people would pick the eighty-five. I know I would, but hopefully, you can have your cake and eat it too and make it to 90 feelings fantastic. So that’s another reason to think about good mitochondrial health.

Viruses, infections and Cellular Energy 

Dr. Ben Boudreau: [00:41:22] Absolutely. And just to touch on a few things because there was a lot, a lot that was mentioned there. But you know, the people who tend to be healthier do tend to be the ones with the most energy, the most muscle. And so it just goes to show, you know, if you can keep your skeletal muscle like Dr. Boudreau, Dr. Rade said. You know, for a longer period of time, then you’ll have that higher energy output. You’ll be able to get more done throughout the day and feel less fatigued. We had a question about flu and illnesses. Maybe just touch on a little bit like if you had the flu, how does that impact your mitochondrial function, for instance, if you’re in that’s within the scope of practice?

Dr. Bryan Rade: [00:42:03] Yeah, for sure. So there’s a lot of interesting things that happen in the body when we’re exposed to an exposed to infection. And one of those things is it actually tells our mitochondria to go into more of a lockdown mode because ultimately viruses, can’t exist like they can’t replicate on their own. They need to hijack our cellular machinery in order to replicate. And so one of the strategies is to go into this lockdown mode where the mitochondria function actually starts to downregulate. And that’s probably part of why we feel just so tired and lethargic and achy and things like, I mean, if you have a fever, that’s going to contribute to ickiness too.

But like, there’s just kind of that muscle heaviness that you just ideally just want to lie in bed. And so there is a component of that mitochondrial dysfunction or other mitochondrial suppression if you will. That’s kind of intentional in that case. What I found is that patients who have nice, healthy mitochondria, they’ll typically lick a virus in a lot faster than the folks who are really depleted. Like, I’ve had so many patients over the years where it’s like, oh, I get sick, and then it takes me like three weeks to get better, like two months to get better.

Dr. Bryan Rade: [00:43:12] Or it always goes to my lungs and turns into bronchitis. Like, Oh my gosh, like, that’s you’re getting knocked out by a simple virus. Like, that’s not good. So oftentimes when you make the mitochondria are more robust, then it will help to improve that overall ability to get rid of the virus. Because of course, it’s shutting down mitochondrial function in certain tissues, like maybe lowering the rate into your muscles, for example. It’s like, Hey, buddy, you need to just stay in bed to fight off this infection as opposed to like going and running all your doing your day-to-day.

Buddhism may be spreading it, making other people sick, too. But your white blood cells, have mitochondria, they need energy in order to replicate and function the other elements of your body, like say that might be needed to generate a fever response that requires energy as well. So if you have a good mitochondria function, to begin with, you’re going to be able to use that ATP to kick that virus to the curb faster. And that’s what I’ve seen many times in practice.

Dr. Clayton Roach: [00:44:13] Dr. Rade, if somebody is feeling well, like if they want to go through those prophylactic treatments like ozone therapy, how often could you do ozone therapy?

Dr. Bryan Rade: [00:44:27] That’s a great question. Yet you could do it like weekly, like when patients come in saying, like, I want to try like I’m feeling good and I want to try some ozone and see if I can feel even better. Then, like a once-a-week treatment for, say, a month would be a really good kick at the can. Ozone therapy is kind of like it’s sort of like with the story of the tortoise and the hare. Ozone can be a little bit tortoise. I usually say to patients, when they’re going to do ozone therapy, it’s like, make sure you give it at least three or four treatments before you judge it because it can take a bit of time because it has this cumulative effect for a lot of people.

High dose nutrient infusion or even a standard dose nutrient infusion that’s like give it one, maybe two treatments. You should see a change within that time if you don’t see a change after one or two. At most, they don’t bother coming in for another one because your body either doesn’t need those nutrients or there’s something that’s blocking your mitochondria and you just can’t use them yet. Like with mitochondrial support, I love it to pieces. I love the comprehensive mitochondrial support. Use it all the time.

Dr. Bryan Rade: [00:45:31] But I’ve had many patients over the years where we give it a try and it doesn’t. It just doesn’t help. Like, you know, we’re going out like we run the testing or this or that, and we’re like, Oh, we’re treating you for mild illness or we’re treating you for some chronic infection. And so you’re on your herbs and you’re doing this and that. And let’s get some mitochondria sort of there to try to jack up your energy. If within a few weeks of being on mitochondrial support, it’s not starting to boost the energy levels in many cases. Also, you know, let’s just side burner that for right now, because we need to do some other things first, to kind of get all the toxic or harmful stuff levels lower so your mitochondria can start working better.

And with some patients to say it’s a mild illness issue, it’s like, well, OK. Even if the mitochondria support isn’t making a big difference with energy, you still should stay on it so you can actually detoxify those toxins. So there are certainly cases where we do persist with it, even if it’s not making a difference with energy quickly. But we should see a change relatively quickly with the nutrient if there’s nothing blocking the mitochondria.

Dr. Clayton Roach: [00:46:29] I think I mean, I think I speak to the crowd here and, you know, correct me if I’m wrong and I probably speak to your patients, a lot of us are thinking, you know, what’s the one thing? What are the two things that I could do to, you know, boost my immune system or to, you know, boost my mitochondria? But there’s nothing like looking at the global picture because, you know, you could throw somebody on ozone therapy, but then you don’t realize that they have, you know, mould or they have, you know, heavy metals.

And so to understand the global picture allows you to build a critical path and figure out where you’re going to get the biggest bang for your buck instead of just going for the, you know, the one solution thing that you think is going to solve everything. So I think the lesson here is to make sure that there is a comprehensive approach and understanding thoroughly what’s going on so that we’re not grasping at the next vitamin or the next mineral and understanding the whole picture. You agree with that Dr. Rade.

Dr. Bryan Rade: [00:47:27] I think it’s well said.

Dr. Clayton Roach: [00:47:29] Yeah, OK,

Dr Ben Boudreau: [00:47:30] So Dr Rade. How can people find you? Because every time that I that we do conversations and you’re on the show, I’m always full of energy and then I give all this energy off to my patients and they’re like, What’s the best way to get in contact with Dr. Rade? I need to see this guy. So how can people get in contact with you?

Dr. Bryan Rade: [00:47:50] Well, I appreciate you saying nice things about me. Dr. Ben, it’s much, much obliged. So you had to get in contact. Our website is East Coast Naturopathic. So in our phone number and email to email contact for my front desk is there. You can email the front desk at East Coast Naturopathic at gmail.com. If folks want to hear me yap about things like if they’re enjoying this like I want to hear, as I talk about other stuff, I do have it an Instagram page. It’s Dr. Bryan Rade, NDI or something like that.

And then I do post them everything on my Facebook page as well. So like on the East Coast naturopathic Facebook page. So yeah, I post as much as I can. It’s always like if I’m finished my patients for the day and managed to answer all the patient emails and I have time to record a video. I do. And then that’s like once a week, maybe on a good week. So but yeah, that’s how they can get in touch with me.

Dr. Clayton Roach: [00:48:49] But have you figured it out? TikTok.

Dr. Bryan Rade: [00:48:52] Oh my gosh, no. Scared of it. I’m scared of TikTok. Yeah. Are you? Are you on TikTok?

Dr. Clayton Roach: [00:48:58] You know what? We did a few TikToks.

Dr. Bryan Rade: [00:49:02] Uh-huh.

Dr. Clayton Roach: [00:49:03] Yeah, great. And they’re actually pretty cool. But you know, it’s, you know, you could waste a lot of time. I don’t want to call it waste, but you know, you could spend a lot of

Dr. Bryan Rade: [00:49:09] Time, you know,

Dr. Clayton Roach: [00:49:11] Hitting every social media platform. It’s tough. It’s tough. At one point, you got to pick the ones that you do.

Dr. Bryan Rade: [00:49:17] Yeah. Yeah, they’re catchy, though, like they’re so visually engaging, but I don’t know how to dance. And so like, it seems like you have to be able to dance in order to do a TikTok, it seems. But so were you guys dancing? No. Ok. No. Never mind that you’re trailblazing the non-dancing TikTok. That’s perfect.

Dr. Clayton Roach: [00:49:37] That might be why we didn’t get a lot of followers.

Dr. Ben Boudreau: [00:49:41] The TikTok handle is Roach Chiropractic Centre.

Dr. Clayton Roach: [00:49:45] Yes, we did do a few. They’re actually pretty cool. We were well planned out. So just, you know, coincidence the internet connection kind of worked out at the end. I can’t thank you enough, Dr. Rade. I know a lot of people have mentioned that these were some of our best conversations. So I really do appreciate the expertise and stuff that you’ve provided to us on these conversations.

One of the things that I had a question from one of my patients today, actually. And she’s not on live tonight, but she is going to watch it is. What are some of the top things that you could mention because winter is coming to boost the immune system and maybe we can end on that and then we’ll kind of close it up? But what can you recommend to boost the immune system during the winter with everything that’s going on as we know?

The top tips to boost immune function with Naturopath Dr. Bryan Rade!

Dr. Bryan Rade: [00:50:35] Yeah, that’s a great question. So I mean, talking to your health care provider, whether it’s your doctor or family doctor, just getting to about getting vitamin D levels checked is something worth considering. I mean, this time of year, hopefully, everyone’s had lots of good sun exposure. And so your vitamin D levels are nicely topped up. Although just this week I had a patient who just had blood work done at the end of August and like her vitamin D level was nowhere near where it should have been, and she was getting lots of sun exposure. So one of the other reasons the genetic testing I mentioned earlier can be useful, as we can look for mutations in the vitamin D receptor gene.

And I’ve noticed a clinical correlation where folks who have certain mutations are the ones who need a lot more vitamin D than the recommended daily amount. So getting vitamin D levels tested like the kind of around January February is, in my opinion, like a good time to get them checked because then you’re a few months out from. Beautiful summer weather, and you can kind of get a sense of how your vitamin D stores are doing. And hopefully, they’re still looking pretty good because heaven knows you still have a good three or four months at that point of, you know, before getting more sun exposure.

So vitamin D, I think it’s really important to stay on top of definitely trying to take good care of oneself in terms of getting enough sleep and good nutrition. All of that. One of the things that I do personally is if I do feel like a sore throat coming on or one of my kids has a cold and it’s I just I know I’m going to be the next victim.

Dr. Bryan Rade: [00:52:00] If I’m not careful, I know I’m extra cautious with my diet. I mean, eating carnivore if there’s just meat. So I don’t really have to worry about sugar and things like that. But back in my day when I was just doing like a boring old paleo diet or like a modified ketogenic diet where there was so much more dietary variety I would really make sure I’m not going to eat things that are sweet. That might rise more carbs because I found that that seemed to, for me at least kind of suppress my immune system a little bit more.

I would also recommend that folks interested in boosting their immune system talk to their health care provider about just certain options for kind of a contingency plan where if you do start getting sick, what can you do to help boost your immune system? I personally trialled a million things over time to see what works the best for me, and I’ve kind of fine-tuned what works for me. But I’ve had so many patients who say, Oh, high dose vitamin C like knocks it out of the park. I start getting sick. I take my high dose of vitamin C. Symptoms go away before they amount too much, and it just works like a charm. And then so many people vitamin C that doesn’t do a blessed thing for them.

Dr. Bryan Rade: [00:53:03] I’ve heard cold FX knocking down the park for some people or oil of oregano, and then for some people, it just doesn’t work at all. So it’s a good idea, in my opinion, to have something in your tool bag because, you know, if it’s just a cold, you know, if you’re not in clinical practise or self-employed and it’s not going to be really tough. Like, where are you going to fit all those patients if you’re down and out for a few days, if you can just be home and be sick like all the power to you, that’s fine?

But if you need to be well because you have kids to take care of or patients to see or whatnot, it’s a good idea to have something in your tool bag because we, we all know someone or maybe experienced ourselves, one of those colds that just won’t go away. It’s just lingering. You got the cough that sticks around for like a couple of weeks. There are some really great tools that can help to nip those things in the bud, but you need to kind of figure out what’s going to work for you. And that’s something that should really be. It would be a lot more efficient. Rather than just buying like 15 things at the health food store and like, I’ll just run through them one at a time. It’s nice to have some guidance, so I’d recommend pursuing that as well.

Dr. Clayton Roach: [00:54:05] That’s well answered. And I think, you know like you said, everybody has a different concoction that works for them because we’re all individuals. This leads me back to say that the global approach and having somebody look at you and look at your whole being and not just looking for that next supplement, I think is important again. And you just summarized it again. So thank you very much. Anything else, Ben.

Dr. Ben Boudreau: [00:54:29] I was just going to say I saw an article and Dr. Rade you’re way better read up on this topic than I am, but we know the importance of vitamin D absorption with K2. But there was also an article that was released about the absorption of vitamin D with proper magnesium levels. And so again, just going with the entire clinical picture and just the importance of making sure that these levels are, you know, at the way that they should be at the level that they should be at. But I just found that it was interesting because, you know, we talk about the importance of magnesium in our practice quite often, especially when it comes to MSK and sleep. But I just thought it was really interesting that correlation between magnesium and vitamin D. Did you hear anything about that or.

Dr. Bryan Rade: [00:55:17] Um, I haven’t seen anything recently about that, but it makes sense because not to sound like a broken record, but you need vitamin D to run your mitochondria properly and you need adequate levels of calcium in your mitochondria to have them run properly and you need vitamin D to absorb calcium. And so I think one of the reasons that some people feel so tired when they are low in vitamin D is probably well, it is related to the mitochondria because they make all the energy for the body. But it’s likely through that calcium component and you need adequate magnesium in order to absorb your calcium as well. So my assumption would be that that’s probably the link there. And yeah, that would be my best guess.

Dr. Clayton Roach: [00:56:04] Yeah. Wonderful. We will end with this. Thank you so much, Dr. Rade, I know we’re a little bit past the hour, so I really appreciate it again. My pleasure, folks. We were very lucky to have somebody that Dr. Rade in our city because a lot of times, you know? To be able to find somebody like this, we need to travel somewhere or do virtual calls, and it’s just not like having somebody in our backyard, so utilize this gentleman for everything that he knows. And you know, if you’ve been around the block and you’re looking for answers that you’re still not getting and the typical traditional medical care, you know, everything is coming back normal and you started thinking on my going crazy and the only is it just me feeling this way?

It probably isn’t, you know, and there’s probably something there that somebody has not explored because traditional testing probably is just not pointing it out. So do yourself a favour. You know, we’re all worthy of being healthy. We’re all worthy of being able to enjoy life’s little pleasures and being able to play with kids and being able to enjoy what we want to enjoy. And I don’t think it’s OK and I see this in practice all the time, Dr. Rade and I’m sure you can attest to this and Dr. Boudreau as well, that sometimes you see people give in to these.

Dr. Clayton Roach: [00:57:21] I don’t know these philosophies that, you know, life ends at 40 and then, oh yeah, you know, it was all true. You know, I hit 40 and it all went downhill and we succumb to that and then we start to live vicariously through that false reality. And then we accept a lower level of life than what we’re, you know, we can be living. So I really thank you for that Dr. Rade. And I know the energy expenditure that goes into creating these somewhat complicated cases. And for that, I thank you so much because we’re in the trenches every day treating people and helping people live to their highest potential, whatever that may be.

So thank you a lot for everything that you’ve done with us, with some of the conversations I really, really appreciated the people that have been living really, really appreciated as well. And maybe a little later on, I’ll feel comfortable bugging you again for another lecture, but we won’t do that for a while. I know you’re busy. I will be personally visiting you for getting some biotech ideas and picking your brain as well. Any closing thoughts? Ben Before we

Dr. Ben Boudreau: [00:58:30] Again, every time that we do these conversations and we have Dr. Rade on the show, I go into work the next day with the newfound not just like a newfound interest for just digging deeper and diving deeper into the situation, so don’t feel lost in the health care system. There are people out there who are here to help, and you can’t let your internal philosophies be a self-fulfilling prophecy of people in the past or who you used to be. Predict who you will become in the future. So make the choice now, make the choice today to have a better tomorrow. And so I believe that Dr. Bryan Rade and Dr. Roach and myself were a part of that solution. So do yourself a favour and take yourself to that next level.

Dr. Clayton Roach: [00:59:17] So, guys, thank you so much. If you’re watching this on YouTube, make sure you subscribe to our channel to check out Dr. Rade at East Coast Naturopathic Center on their website as well, and maybe make this you know your gift for this year. You don’t get an assessment done. And instead of making a Crazy New Year’s resolution, seek the help of a professional that’s just right in our backyard. Dr. Rade Thank you so much.

Dr. Bryan Rade: [00:59:42] Thank you both. It’s been a pleasure.

Dr. Clayton Roach: [00:59:45] All right. We’ll talk next week, 9:00 o’clock for Humpday Conversation number forty-seven. Enjoy a week. Enjoy fall. The weather’s still nice and we will talk soon. Take care, guys, and good night. What’s up, guys? Listen, if you like this episode, you’ll probably like the other ones. Channels are pretty good, so here’s what you need to do. You need to like us and follow us on Facebook. Following means, you get notified when these two guys are alive. Next, family, friends. You need to share these episodes because you never know you might help them because they need this information as well. And guys, if you ever miss an episode, make sure you subscribe to us on YouTube. That way, you can watch the episode over and over and over again. Guys, we love you and appreciate you. Take care.